Abstract: Objective To investigate the surgical treatment and postoperative quality of life in locally advanced thyroid carcinoma with tracheal invasion and intravascular tumor thrombus. Methods The clinical presentation, auxiliary examinations, diagnosis and treatment process, and prognosis of one case of locally advanced thyroid carcinoma were retrospectively analyzed, along with a review of relevant literature. Results An elderly female patient diagnosed with thyroid carcinoma complicated by tracheal invasion and intravascular tumor thrombus underwent surgical treatment directly following a multidisciplinary discussion. The tumor and surrounding invaded areas were completely resected through a collaborative effort involving departments of thyroid surgery, otolaryngology, vascular surgery, and anesthesiology. At 16 months of postoperative follow-up, the patient has a favorable prognosis, remains in disease-free survival status, and shows no evidence of local recurrence or distant metastasis. Conclusion Surgical treatment is one of the effective methods for managing locally advanced thyroid carcinoma. Preoperative risk stratification assessment and multidisciplinary discussions are beneficial for formulating appropriate treatment plans. Multi-department collaboration can enhance surgical outcomes and improve the patient′s postoperative quality of life.

Key words: locally advanced, thyroid carcinoma, risk stratification, multidisciplinary discussion, quality of life

摘要： 目的 探讨局部晚期甲状腺癌（气管侵犯伴血管内癌栓）的外科治疗及术后生活质量。方法 回顾性分析1例局部晚期甲状腺癌患者的临床表现、辅助检查、诊疗经过以及预后,并复习相关文献。结果 老年女性患者诊断考虑甲状腺癌合并气管侵犯和血管内癌栓,经多学科讨论后决定直接行手术治疗,经甲状腺外科、耳鼻喉科、血管外科、麻醉科等多科室协作下,完整切除肿瘤和周围侵犯区域,术后随访16个月,患者预后良好,处于无病生存状态,无局部复发或远处转移征象。结论 手术治疗是治疗局部晚期甲状腺癌的有效方法之一,术前进行危险分层评估和多学科讨论有益于制订合理的治疗方案,多科室联合能够提升手术效果,改善患者术后生活质量。

关键词: 局部晚期, 甲状腺癌, 危险分层, 多学科讨论, 生活质量