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岭南现代临床外科 ›› 2025, Vol. 25 ›› Issue (04): 227-231.DOI: 10.3969/j.issn.1009-976X.2025.04.003

• 论著与临床研究 • 上一篇    下一篇

基于3D可视化重建的腹腔镜下剜除术对肾错构瘤患者手术失血、肝肾功能和创伤应激的影响

张发标, 廖尚范, 周文湖, 连周彪, 朱仁文   

  1. 福建医科大学附属三明市第一医院泌尿外科,福建三明 365000
  • 通讯作者: 张发标,EMAIL:1980451571@qq.com
  • 基金资助:
    福建省自然科学基金项目(2020J011272)

Influence of laparoscopic enucleation based on 3D visualization reconstruction on surgical blood loss, liver and kidney function and traumatic stress in patients with renal angiomyolipoma

ZHANG Fa-biao, LIAO Shang-fan, ZHOU Wen-hu, LIAN Zhou-biao, ZHU Ren-wen   

  1. Department of Urology, Sanming First Hospital Affiliated to Fujian Medical University, Sanming, Fujian 365000, China
  • Published:2025-09-26

摘要: 目的 探究基于3D可视化重建的腹腔镜下剜除术对肾错构瘤患者手术失血、肝肾功能和创伤应激的影响。方法 回顾性分析2020年1月至2025年1月本院收治的肾错构瘤患者临床资料,将行常规腹腔镜手术的肾错构瘤患者纳入对照组(42例);将行基于3D可视化重建的腹腔镜剜除术的肾错构瘤患者纳入研究组(40例)。比较两组手术相关指标及术后并发症发生情况,评估术前、术后24h两组患者肝功能指标[谷丙转氨酶(ALT)、谷草转氨酶(AST)]、肾功能指标[血清肌酐(SCr)、肾小球滤过率(eGFR)]、血清创伤应激指标[总抗氧化能力(TAC)、缺血修饰白蛋白(IMA)、肌红蛋白(MYO)]水平。结果 研究组手术时间和住院时间均较对照组显著缩短(均P<0.05),但术中肾动脉阻断时间和出血量比较差异无统计学意义(均P>0.05)。术后24 h,两组患者血清ALT、AST、SCr、IMA、MYO均高于术前水平(P<0.05),研究组血清SCr、IMA、MYO指标水平均低于对照组(均P<0.05),但研究组与对照组血清ALT、AST指标比较差异无统计学意义(P>0.05);两组患者eGFR及TAC指标均低于术前,但研究组eGFR及TAC水平均高于对照组(P均<0.05);两组患者术后并发症发生率比较差异无统计学意义(P>0.05)。结论 基于3D可视化重建的腹腔镜下剜除术有助于减轻肾错构瘤患者手术造成的肾损伤及创伤应激反应,对缩短手术时间及患者住院时间有积极影响,3D可视化重建技术作为辅助手术技术具有推广价值。

关键词: 3D可视化重建, 腹腔镜剜除术, 肾错构瘤, 肝肾功能, 创伤应激

Abstract: Objective To explore the influence of laparoscopic enucleation based on 3D visualization reconstruction on surgical blood loss, liver-kidney function and traumatic stress in patients with renal angiomyolipoma. Methods The clinical data of patients with renal angiomyolipoma admitted to the hospital from January 2020 to January 2025 were retrospectively analyzed. 42 patients with renal angiomyolipoma who received conventional laparoscopic surgery were included in control group, and 40 patients with renal angiomyolipoma who underwent laparoscopic enucleation based on 3D visualization reconstruction were included in study group. The surgery-related indexes and occurrence of postoperative complications were compared between the two groups, and the liver function indexes [alanine aminotransferase (ALT), aspartate aminotransferase (AST)], renal function indexes [serum creatinine (SCr), glomerular filtration rate (eGFR)] and serum traumatic stress indexes [total antioxidant capacity (TAC), serum ischemia modified albumin (IMA), myoglobin (MYO)] were evaluated in the two groups of patients before surgery and at 24 hours after surgery. Results The surgical time and hospitalization time in study group were significantly shortened compared with than those in control group (all P<0.05). There were no statistical differences in the renal artery clamping time and blood loss during surgery between the two groups (all P>0.05). At 24 hours after surgery, serum ALT, AST, SCr, IMA and MYO in the two groups were higher than those before surgery, and the levels of serum SCr, IMA and MYO in study group were lower than those in control group (all P<0.05). However, there were no statistical differences in serum ALT and AST between study group and control group (P>0.05). The eGFR and TAC in the two groups were lower than those before surgery, and the eGFR and TAC were higher in study group than those in control group (all P<0.05). There was no statistical significance in the incidence of postoperative complications between the two groups (P>0.05). Conclusion Laparoscopic enucleation under 3D visualization reconstruction is helpful to relieve the renal injury and traumatic stress response caused by surgery in patients with renal angiomyolipoma, and has a positive effect on shortening the surgical time and hospitalization time. As an auxiliary surgical technique, 3D visualization reconstruction technology has promotion value.

Key words: 3D visualization reconstruction, laparoscopic enucleation, renal angiomyolipoma, liver-kidney function, traumatic stress

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