关键词: 重症急性胰腺炎, 吉兰-巴雷综合征, 多学科团队诊疗

Abstract: Severe acute pancreatitis is a disease caused by local inflammation, necrosis and infection of the pancreas caused by a variety of causes,accompanied by systemic inflammatory response and persistent organ failure. Guillain Barre syndrome （GBS） is a type of immune-mediated acute inflammatory peripheral neuropathy. It has an acute onset and usually reaches its peak in about 2 weeks. Clinically, symmetrical flaccid limb paralysis, facial nerve paralysis, peripheral sensory impairment,and “protein-cell” separation in cerebrospinal fluid are common. GBS is common after infection,and it has also been reported to be combined with other diseases. This article reports a rare case of a 42-year-old male patient with severe necrotizing pancreatitis complicated by Guillain Barre syndrome. After comprehensive treatment by a multidisciplinary team （MDT）,the patient′s pancreatitis-related symptoms and neurological symptoms were improved to some extent. For patients with central nervous system symptoms,clinical practice needs to be more vigilant to consider the possibility of Guillain Barre syndrome,achieve early identification and intervention,and improve the patient′s prognosis.

Key words: severe pancreatitis, guillain barre syndrome, multi-disciplinary treatment