关键词: 肺磨玻璃结节, 体层摄影技术, X线计算机

Abstract: Objective To evaluate the diagnostic ability of the mean CT value for pulmonary ground glass nodules which were less than 1 cm. Methods We retrospectively evaluated 216 patients with ground glass nodules less than 1 cm between 2016 and 2020. All these ground glass nodules were resected and pathologically diagnosed. The mean CT value were measured in picture archiving and communication system（PACS） and its optimal cut-off point for the mean CT value was analyzed with receive operating characteristic（ROC） curve. Results The mean CT value of inflammatory lesion group was -782 ~ -377（-595.9±122.3） Hounsfield units（HU）, which was lower than lung adenocarcinoma group which the mean CT value was -807 ~ -57（-494.3±157.4）HU（t=-2.190,P<0.05）. The cut-off point was -604 HU, the sensitivity was 73.5% and the specificity was 67.3%, the area under curve（AUC） was 0.69. The mean CT value of the preinvasive group was -807 ~ -111（-540.1±131.1）HU, and The mean CT value of the invasive group was -807 ~ -57（-464.8±166.2）HU. The difference between the two group statistically significant （t=-2.66,P<0.05）. The cut-off point was -473 HU, the sensitivity was 50.8% and the specificity was 75%, the AUC was 0.64. Conclusion Themean CT value is valuable in the differential diagnosis of benign and malignant lesion in the ground glass nodules which was less than 1 cm, and it is helpful to judge the invasiveness of the lung adenocarcinoma.

Key words: lung ground glass nodules, tography, X-ray computer