Abstract: Objective To investigate the clinicopathological features of hepatic alveolar echinococcosis. Methods The clinical, pathological, and imaging data of one case of hepatic alveolar echinococcosis were retrospectively analyzed. HE （hematoxylin-eosin） staining slides were observed for surgical resection, and the pathological tissue morphological characteristics were analyzed, and relevant literature was reviewed. Results The Gross examination showed cystic mass in the liver. Histologically, the liver tissue was purulent, and large necrosis and granuloma formation were seen, some vesicular larvae vesicles of different sizes were seen in the necrotic tissue, and the vesicular larvae vesicles were only seen in the corneal cortex, which showed that there was no structure in the red staining uniform, and no germinal layer was seen. Conclusion Hepatic alveolar echinococcosis is rare in low-incidence areas, and most of the lesions are atypical when erythrotic vesicle-like structures can be seen in the background of hepatic necrotizing granulomatous inflammation, is necessary to be vigilant against the possibility of hepatic alveolar echinococcosis in combination with epidemiological history, imaging, and laboratory examination results, to avoid missed diagnosis and misdiagnosis.

Key words: liver, alveolar echinococcosis, low-incidence areas, pathologic features

摘要： 目的 探讨肝泡状棘球蚴病临床病理学特征。方法 回顾性分析1例肝泡状棘球蚴病的临床和影像学资料,对手术切除肝肿物苏木精-伊红（HE）染色玻片进行观察,分析其病理组织形态特征,并进行相关文献复习。结果 大体检查可见多个肝囊状肿块,镜检肝组织呈多灶性化脓性炎症,伴大片坏死及肉芽肿形成,坏死区内见一些大小不等的泡状蚴子囊泡,仅见角皮层,呈红染一致性无结构物,未见生发层。结论 低发病区的肝泡状棘球蚴病少见,且大部分病变形态不典型,在肝脏坏死性肉芽肿性炎背景中可见红染的囊泡状结构时,需结合流行病学史、影像学及实验室检查结果等,警惕肝泡状棘球蚴病可能,避免漏诊误诊。

关键词: 肝脏, 泡状棘球蚴病, 低发病区, 病理学特征