Abstract: ［Abstract］ Objective To investigate the effect of ischemia on epiphyseal plate of proximal fibula. Methods Twelve young rabbits of 8 weeks old were randomly divided into 3 groups. The proximal blood vessels of the fibula were carefully exposed according to the cutting method of transplantation of fibula with epiphysis. The blood supply to the proximal epiphysis of the fibula was blocked by 0， 1 and 1.5 hours by blocking the right common iliac vessels. X-ray examination was performed every week after operation to observe and record the time of epiphyseal closure of fibula. Statistical analysis was used to compare the closure time of fibula epiphysis in each group. Results the closure time of epiphysis in 0 hour ischemia group was 8.25±0.71 weeks， the closure time of epiphysis in 1 hour group was 8.13+0.99 weeks， and the closure time of epiphysis in 1.5 hour ischemia group was 8.13±0.99 weeks. There was no significant difference in the closure time between the three groups （P>0.05）. Conclusion In the process of epiphyseal fibula transplantation， if the time of epiphyseal ischemia is controlled within a certain time， the short term epiphyseal ischemia would not lead to premature closure of epiphysis.

Key words: rabbits, proximal fibula, ischemia, epiphysis

摘要： ［摘要］ 目的 探讨腓骨近端骨骺缺血对骺板影响。方法 选择8周龄幼兔12只，随机分成3 组，分别对幼兔小腿按照带骨骺腓骨移植时腓骨头切取方法细心分离双侧腓骨近端及血管。通过阻断髂总血管方法对腓骨近端骨骺血供分别阻断0、1和1.5小时。术后每周复查X线，观察并记录各幼兔腓骨头骨骺闭合时间。用统计学方法对各组腓骨骨骺闭合时间进行统计学比较分析。结果 缺血0小时组骨骺闭合时间为8.25±0.71周，缺血1小时组骨骺闭合时间为8.13±0.99周，缺血1.5小时组骨骺闭合时间为8.13±0.99周。三组腓骨骨骺闭合时间无明显差异（P>0.05）。结论 在带骨骺腓骨移植过程中骨骺缺血时间控制在一定时间范围内，骨骺短期的缺血不会导致骨骺早闭。

关键词: 缺血, 骨骺, 腓骨近端