关键词: 纳米碳淋巴示踪技术, 胆道损伤, 腹腔镜胆囊切除术

Abstract: Objective To investigate the feasibility and application value of carbonnanoscale lymph node tracing technique in complex and difficult cholecystectomy. Methods This study was a single-center, single-blind, randomized controlled clinical trial. Patients diagnosed with cholecystolithiasis with cholecystitis admitted to the Department of Hepatobiliary Pancreatic Minimally Invasive Surgery of Yuebei People's Hospital from January 2022 to December 2022 were recruited. Sixty subjects were collected according to the inclusion and exclusion criteria, and were divided into the study group and the control group with 30 cases in each group by random number table method. The study group received laparoscopic cholecystectomy （LC） combined with carbon nanoscale lymph node tracer, and the control group received conventional LC. Gender, age and other general basic data of the two groups were compared, and the incidence of postoperative complications, exposure time of the gallbladder triangle, and intraoperative blood loss were used as outcome indicators. Results Among the two groups, the study group was not inferior to the control group in terms of postoperative exhaust time, intraoperative bleeding, exposure time of gallbladder triangleand total hospitalization cost, but had no significant difference with the control group. The total complication rate of the study group （6.66%） was as that of the control group （13.33%）, with no significant difference. Conclusion Nano-carbon tracer technology can assist in locating the anatomical relationship of gallbladder triangle in complex and difficult cholecystectomy, with strong feasibility and safety. Compared with LC alone, it has advantages in reducing bleeding and reducing complication rate, and is worth promoting and applying in clinical practice.

Key words: nano-carbon lymphatic tracer technology, biliary tract injury, laparoscopic cholecystectomy