关键词: 疗效, 骨质疏松, 椎体压缩性骨折, 经皮椎体成形术

Abstract: 【Abstract】 Objective To evaluate the effect of percutaneous vertebroplasty （PVP） on osteoporotic vertebral compression fracture （OVCF）. Methods Thirty-six patients with OVCF（single vertebral fracture） from Jan 2011 to June 2014 in our hospital undergoing PVP were retrospectively analyzed. The average age of the patients was 74 years. The extent of pain was measured with visual analog scale, and the compression ratio, the kyphotic angle and the complications were also investigated. Results A remarkable pain relief was achieved within 24 hours postoperatively in all cases. Postoperative VAS values declined markedly and were statistically significantly different from preoperative values （P<0.001）. No statistically significant differences were recorded between preoperative and postoperative values of compression ratio or kyphotic angle （P>0.05）. Asymptomatic cement leakage was found on postoperative radiographs in four cases. All cases were followed from 24 to 42 months, 33 months at average. Adjacent vertebral fractures were confirmed by X-ray in four cases within 2 years and lumbar back pain were manifested. No pain exacerbation or fresh onset of neural compression took place in the rest of patients. The form of neither the responsible vertebrae nor their adjacent vertebrae had changed. Conclusion PVP is a safe and effective method for treating OVCF.

Key words: Percutaneous vertebroplasty, Vertebral compression fracture, Effect, Osteoporosis