Progress on the prognosis prediction of hepatocellular carcinoma after liver resection

doi:10.3969/j.issn.1009-976X.2021.04.021

Abstract

Abstract: Hepatocellular carcinoma （HCC） is one of the most common malignant neoplasms in the digestive system and surgical resection is an important method to treat HCC. However, the biological characteristics of HCC determine that there is still a high rate of metastasis and recurrence after radical resection,which finally leads to poor prognosis. Therefore, exploring the prognostic predictive factors for HCC after liver resection will be helpful to provide a more comprehensive reference for the formulation of surgical plans and the selection of postoperative adjuvant treatment measures. This article will review the relevant progress of prognosis prediction of HCC after liver resection from the aspects of tumor staging system, immune-inflammation-related indicators, serum tumor markers, non-coding RNA, liver function, imaging features and clinical models.

Key words: hepatocellular carcinoma, hepatectomy, prognosis, predictive factors

摘要： 肝癌是消化系统最常见的恶性肿瘤类型之一,手术切除是治疗肝癌的重要方法。但是,肝癌的生物学特性决定了根治性切除术后仍存在较高的转移复发率,导致患者预后不佳。因此,探索并筛选肝癌切除术后预后预测的相关因素,将有助于为手术方案的制定和术后辅助治疗措施的选择提供更全面的参考依据。本综述将从肿瘤分期系统、免疫炎症相关指标、血清肿瘤标记物、非编码RNA、肝功能、影像学特征和临床模型等方面,对肝癌切除术后预后预测的研究进展做一综述。

关键词: 肝癌, 肝切除术, 预后, 预测因素

CLC Number:

R735.7

WANG Qing-bin, SHANG Chang-zhen, CHEN Ya-jin. Progress on the prognosis prediction of hepatocellular carcinoma after liver resection[J]. Lingnan Modern Clinics In Surgery, 2021, 21(04): 471-476.

王庆斌, 商昌珍, 陈亚进. 肝癌切除术后预后预测的研究进展[J]. 岭南现代临床外科, 2021, 21(04): 471-476.

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