关键词: 基因, 靶向治疗, 诊断, 甲状腺乳头状癌

Abstract:

【Abstract】 Thyroid carcinoma is the most common malignant tumor of endocrine organs. Papillary thyroid carcinoma accounts for approximately 90% of thyroid cancers. While most tumors can be diag-nosed and treated without much difficulty, a few tumors, sometimes still pose some diagnostic or thera-peutic challenges. Advances in the understanding of the genetic and biologic characteristics of thyroid papillary cancer, coupled with the development of new molecular targeted therapeutics, have led to the improved diagnosis and treatment of patients with this cancer. In the current review, we summarize re-cent research on genetic characteristics of the thyroid papillary cancer and their importance for the devel-opment of tumor.

Key words: Papillary thyroid carcinoma, Targeted therapy, Gene, Diagnosis